Kutheni iCryovials ibalulekile ekuGcineni isampulu yexesha elide
Iibhotile ze-Cryogenic zezona zixhobo zisetyenziswa yi-biotech, amayeza kunye neelebhu zophando ukugcina iisampuli ixesha elide ngenxa yokuba zibonelela ngesiqinisekiso. Oku kuyalela ukuba ukubanjwa komkhenkce kwiibhotile ezizodwa ziyakwazi ukukhusela iiseli, izicubu kunye nolwelo kwiminwe enomkhenkce. I-cryovial ene-cap engangeni moya ukukhusela ukuphelelwa ngamanzi emzimbeni kunye nokwakheka komkhenkce okunokunciphisa ukusebenza kweeseli. Ukongeza, banokungena okumanzi okuphantsi kakhulu kunye negesi ephantsi kakhulu / ukungena okungcolisayo okubenza babe yinkqubo efanelekileyo yokugcina isampulu.
Njengoko ii-vials ze-cryogenic zenziwe ngezinto ezahlukeneyo, ziza kuluhlu olukhulu lobungakanani kunye neempawu kunye nokugcinwa okukhuselekileyo kokusebenza kunye nobomi beshelufu bunokuboniswa ukuba buxhomekeke kwezi + nezinye izinto ezininzi ezingaziwayo. Ke ngoko, malunga nokukhethwa kwe-vial ye-cryogenic ezininzi izinto zithathelwa ingqalelo malunga nohlobo lwesampulu egciniweyo kunye nokuba kufuneka igcinwe ixesha elingakanani ngaphambi kokuba isetyenziswe ukubhanqa noyilo lwesikhongozeli kunye nokuhambelana nezinye iitekhnoloji. Oku kubandakanya, nangona kungaphelelanga kwiindlela ezifanelekileyo zokuleyibheli kunye neendlela zokulandelela ezikwakhona ukulungiselela ukhuseleko oluyimfuneko olusebenzayo okanye olungenziwayo kumanqanaba ogcino (Umzekelo, ukuphatha/uthutho/ukutshatyalaliswa njl.njl.).
Kwimibhobho yanamhlanje ye-cryogenic, uyilo luya kusebenzisa izinto ezikumgangatho ophezulu kunye nemigaqo yobunjineli ukuqinisekisa ukuba iisampulu zinokukhenkcezwa / zinyibilikiswe okanye zithuthwe ngelixa zihleli kwaye zisebenza. Inyathelo elikhulu elithathiweyo kuphuhliso lwetekhnoloji ye-cryogenic vial kukuba neegaskets ezikhethekileyo ze-silicone kunye ne-o-rings eyenzelwe ukubonelela ngesitywina esihambelanayo sokuvuza. Oku kunceda ngokucacileyo iisampuli ukusuka kungcoliseko lwezinto zangaphandle ngokunjalo. Abasebenzisi banokufunda ngokulula imisonto yangaphandle kwezi vial ngaphandle kokufuna nayiphi na ingxaki, oku kuthetha ukuba kukho amathuba asezantsi ongcoliseko kunye nenkcitho. Ngaphezu koko, ukwakhiwa kwi-polypropylene kwenza ubushushu obuphantsi kunye nokuchasana kwempembelelo emva koko kukhuseleke ngokugqibeleleyo iisampulu ngaphandle kokulahla ingqibelelo yesampulu.
Uphuculo olutsha kwitekhnoloji ye-cryogenic vial iye yaphuhliswa ukuqhubela phambili amanqanaba okhuseleko lwesampulu, ukusebenza kunye nokuzinza. Ukusetyenziswa iipolymers ezintsha ezifana ethylene tetrafluoroethylene (ETFE) kunye ne-fluoralkoxy alkane nganye, iye yavumela ukuba uphuhliso glasslike robust iingqayi akwazi ukumelana nezi meko ezinzima kakhulu. Iphinde yanciphisa isampuli elahlekileyo kunye nomthwalo wolawulo lomsebenzi ngokusetyenziswa kwelebhile ye-RFID yokulandelela iisampulu ezizenzekelayo. Izikhuselo zi-semisoft, azinakukuthintela konke ukukhanya ngaphandle kodwa kuye kwakhanyisa isixa esincinci sokukhanya ukufikelela kwiisampulu kwaye kuthintele ukuthotywa kwesampulu ngesiqulathi esithe ngqo ngaphezulu kokugcinwa kweentsuku ezininzi.
Ngaphandle kokugcinwa kwe-cryopreservation, ugcino lwenitrogen engamanzi kunye nendlela yokukhenkcisa yolunye uhlobo nayo inokusetyenziselwa ukugcina iisampulu njengeengqayi ezifanelekileyo zefomu encinci. Izazinzulu zifuna ngokwenyani ukuba ugcino lwazo lweekhemikhali lusetyenziswe ngexesha leenkqubo ezahlukeneyo kwilebhu ezinjengokulima iiseli, ukuhlela, ukuvala inzala kunye ne-centrifugation; ngoko ke kubalulekile ukuba ivial elungileyo ye-cryogenic isebenze kwincopho yayo ngeenjongo zonke ukuze ukhuseleko lungachaphazeleki ngelixa ukuchaneka kunyuswa kukhokelela ekusebenzeni kakuhle xa usebenzisa iisampulu. Uninzi lwezi zixhobo zebhayoloji zikwagcina iingqayi ze-cryogenic ezisetyenziselwa ukugcina inani leisampulu zebhayoloji ezinjengokutya, igazi kunye nezinye izinto ezibaluleke kakhulu kwimiba yempilo yoluntu okanye kwizifundo zesayensi.
Ngamafutshane, Xa iisampulu zebhayoloji kunye nezakhemikhali zigcinwa kwi-cryovials zigcinwe kwiqondo lobushushu eliphantsi ixesha elide ukuze kuqinisekiswe ukuba ukusebenza kwazo kugcinwe ngendlela yokukhenkceza; kuthetha ukuba zigcinwe ngomgangatho othile. Ukongeza ukuzinzisa iiseli kwindawo yokugcina ehambelanayo ye-NBF egcina ukusebenza ukuya kuthi ga kwi-15h kwezi teknoloji zesizukulwana esitsha ze-cryogenic vial zibandakanya iipolymers eziphucukileyo ngaloo ndlela zinikezela ukuxhathisa ukothuka okushushu, kunye nokuphinda ukusebenza komkhenkce / ukunyibilika: ezinye zine-RFID+ bar-coding ehambelanayo okanye ikhaka elikhuselayo lokukhanya. ukukhusela i-photosensitive specimen - zonke zinegalelo kwiinzuzo ezongezelelekileyo ezandisa i-frizen-transit-thawing isivalo setyhubhu esiqhwatyiweyo sisebenzise uzinzo olucacileyo oluhambelana ne-pve-CHO yovavanyo lweseli ye-identity gains return kwi-CDE efunyenweyo. Iziphumo ezilungileyo zifumaneka ngokuthathela ingqalelo uhlobo lweesampulu, ixesha lokugcina, umgangatho kunye nobudlelwane kunye noyilo lwesikhongozeli ekukhetheni i-vial cryogenic. Iingqayi zeCryogenic zinomtsalane ngenxa yokuguquguquka kwayo njengoko inokusetyenziselwa uninzi lweenkqubo zaselabhoratri kunye nophando.
iimveliso ziye zaqinisekiswa CE, FCC SGS. Senza uhlolo olungenayo kunye nokuhlola imveliso ngaphandle kwe-intanethi enye ngexesha. i-cryogenic vialspart yeemveliso iza ne-QC yayo. bonelela ngemimiselo yewaranti eyahlukeneyo yeemveliso ezahlukeneyo. Iziqinisekiso ezithile imveliso nganye zinikezelwa.
Ngobudlelwane bentsebenziswano bezizwe ngezizwe obuhlala ixesha elide, amava abanzi okuthumela ngaphandle kunye ne-cryogenic vialsteam yabathengisi bangaphandle inkqubo yenkxaso ebanzi emva kokuthengisa inokunxibelelana nawe ngokukhawuleza nangokufanelekileyo, kunye nokuhlalutya ulwazi lwentengiso, njalo njalo.
Umgangatho yeyona nto ibalulekileyo kwimpumelelo. Imfezeko ingundoqo kwintsebenziswano ephindwe kabini. Ngetyala eliphezulu i-cryogenic vials kunye neemveliso ezikumgangatho ophezulu, inkqubo yenkonzo kunye nomgaqo-nkqubo wamaxabiso okhuphisanayo, sijonge ngokunyanisekileyo ukwakha oluzinzileyo, ubudlelwane bexesha elide lobuchule beshishini kuwe.
bambelela kumsebenzi wokulawula umgangatho ongqongqo wokuqinisekisa ukuba imveliso ikumgangatho ophezulu. Inkampani i-cryogenic vials ifunda itekhnoloji entsha ngaphakathi nangaphandle ukunyusa umgangatho weemveliso zayo.
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